NOTE: This test is ONLY AVAILABLE TO AUSTRALIAN RESIDENTS.
Do you have a methylation problem?
Methylation is a process where certain nutrients called ‘methyl donors’ are added to specific elements of DNA, our gene markers and proteins that keep them physiologically active. Methylation is a major pathway to focus on in understanding autoimmune and neurological diseases such as multiple sclerosis, seizure disorders, dementia, chronic fatigue syndrome, lupus, depression, anxiety and autism spectrum disorders. Methylation is responsible for making, maintaining and repairing DNA.
The methylation cycle is a biochemical pathway that manages or contributes to a wide range of biochemical functions: detoxification, supporting DNA (turning genes on and off), producing energy, reducing inflammation, synthesising neurotransmitters, homocysteine metabolism, protein methylation, phase 2 liver detoxification and supporting immune function. Inadequate methylation capacity can lead to birth defects, depression, cognitive decline, and cancer. Impaired methylation has even been associated with autism. Support of methylation markers has been associated with rapid return of speech, improvement of behaviour in ADD and ADHD spectrums.
Analytes
- 5-methyl tetrahydrofolate (5MTHF)
- Folinic acid
- S-Adenosyl Homocysteine (SAH)
- S-Adenosyl Methionine (SAMe)
- SAMe:SAH ratio
- Tetrahydrofolate (THF)
Test Method
LCMS/MS/MS (Liquid chromatography mass spectrometry)
Symptoms of methylation problems
Inadequate methylation capacity can lead to birth defects, depression, cognitive decline, cancer & detoxification problems such as heavy metal toxicity. Impaired methylation has even been associated with autism. Support of methylation markers has been associated with rapid return of speech, improvement of behavior in ADD and ADHD. Methylation problems are a big problem and are associated with a large number of health concerns, click here to see a full list of symptoms associated with methylation problems such as under and over methylation.
About The Test
All tests come with full instructions, including a pre-authorised practitioner script.
Home test kits come with everything you need to complete the test, including free express post return postage to the laboratory.
All pathology test kits come with a preauthorised script (including test kit/s if required) to take to your local pathology test centre.
You can click here to find a pathology near you.
Turn-around time: 18 days
More about methylation
Methylation is a process where certain nutrients called ‘methyl donors’ are added to specific elements of DNA, our gene markers and proteins that keep them physiologically active. Methylation is a major pathway to focus on in understanding autoimmune and neurological diseases such as multiple sclerosis, seizure disorders, dementia, chronic fatigue syndrome, lupus, depression, anxiety and autism spectrum disorders.
Methylation is responsible for making, maintaining and repairing DNA. People with MTHFR gene mutations often have methylation problems and benefit greatly from methylation testing.
Have any questions about this test? Ask one of our qualified health practitioners here.
