M2 Pyruvate Kinase (M2-PK) Stool Test




M2 Pyruvate Kinase (M2-PK), as measured in faeces, is a tumour marker for colorectal cancer.  Though M2-PK can be elevated in many tumour types, rather than being an organ-specific tumour marker, increased stool (faecal) levels can be used as a early detection of colorectal carcinomas.

The detection of M2-PK does not depend on blood in the stool and is specifically related to changes in tumour metabolism. The M2-PK test is a non-invasive stool test that can be used for the early detection of colorectal cancers and polyps which are known to be the precursors of colorectal cancer.

Increased M2-PK values can sometimes also occur in severe inflammatory diseases which must be excluded by differential diagnosis. If elevated levels of M2PK are present, it is recommended to request more specific tumour marker tests such as (CEA) for bowel cancer, CA 19-9 for pancreatic cancer and CA 72-4 for gastric cancer. This will significantly increase the sensitivity to detect various cancers.

M2PK can be ordered as a single marker or in alliance with a CDSA panel that includes certain GIT markers.

Common Conditions:

  • Bloating, pain or nausea
  • Blood detected in stool sample
  • Loose or watery stools
  • Undigested food in the stool
  • Hypochlorhydria
  • Food intolerances
  • Gastroesophageal reflux symptoms
  • Diabetes
  • Cholecystectomy
  • Osteoporosis

About The M2 Pyruvate Kinase (M2-PK)

After you purchase the M2 Pyruvate Kinase (M2-PK) test, you will receive a simple stool test kit in the mail.

The test is a simple home test kit that enables you to take stool samples using the kit and instructions provided, the kit includes everything you need to take the test at home and includes express postage to send your test samples back to the laboratory.

Test results are sent to one of our professional health practitioners within 5 business days for evaluation.  Our practitioners contact you with the results and recommendations on any findings via email, mail or phone.

Have any questions about this test?  Ask one of our qualified health practitioners here.