The Sleep Hormone Saliva Test
The Sleep Profile is a non-invasive saliva test that assesses two major causes for insomnia: imbalances in melatonin and cortisol. Melatonin is a peptide hormone produced by the pineal gland which helps to control normal sleep patterns. Deficiencies of this hormone can lead to insomnia; however melatonin supplementation can effectively treat this problem if diagnosed correctly. Imbalances in the diurnal pattern of the glucocorticoid hormone cortisol can also lead to sleep disturbances.
Insomnia is defined as a repeated difficulty with sleep initiation, maintenance, duration and/or quality of sleep. This occurs despite adequate opportunity and time for sleep and results in daytime impairment. Mild (transient or short-term) insomnia is known to affect between 30-50% of the general population, whilst chronic insomnia has a prevalence of 9-15%. This disorder affects energy levels, memory, concentration and problem solving skills. In addition, it has been linked to learning disabilities in children. Sleeplessness not only affects the individual but also produces social stress, lowered employee productivity and higher number of accidents. Therefore it is vital that the cause and treatment of insomnia is adequately addressed.
Analytes
- Cortisol (12-2am)
- Melatonin (12-2am)
- Midnight Collection (Preferably in the dark)
Test Method
EIA (Enzyme immunoassay), RIA (Radio immunoassay)
About The Test
All tests come with full instructions, including a pre-authorised practitioner script.
Home test kits come with everything you need to complete the test, including free express post return postage to the laboratory.
All pathology test kits come with a preauthorised script (including test kit/s if required) to take to your local pathology test centre.
You can click here to find a pathology near you.
Turn-around time: 3–5 days
Symptoms of Melatonin Deficiency
- Mental and Emotional Health
- Cardiovascular Health
- Other Health Conditions
- Fatigue
- Hair loss
- Headaches
- Insomnia
- Shift work
Insomnia
Insomnia is defined as repeated difficulty with sleep initiation, maintenance, duration, and/or quality of sleep. This occurs despite adequate opportunity and time for sleep, and results in daytime impairment. Mild (transient or short-term) insomnia is known to affect between 30 – 50% of the general population, whilst chronic insomnia has a prevalence of 9 – 15%. This disorder affects energy levels, memory, concentration and problem solving skills. In addition, it has been linked to learning disabilities in children. Sleeplessness not only affects the individual but also produces social stress, lowered employee productivity, and a higher number of accidents. Therefore it is vital that the cause and treatment of insomnia is adequately addressed.
Melatonin, Anti-aging, and Sleep
Melatonin is a peptide hormone produced in the brain by the pineal gland from the amino acid tryptophan. It regulates the body’s circadian rhythms helping to control normal sleep patterns. It is highest in the body at night and lowest during the day. The synthesis of this hormone in humans is stimulated by darkness and suppressed by light. Melatonin supplementation has been used for assisting sleep in insomniacs, shift-workers and those dealing with jetlag. In addition, conditions that are associated with poor sleep, such as Alzheimer’s disease, attention deficit hyperactivity disorder (ADHD), irritable bowel syndrome, and depression, are also assisted by melatonin use.
Results show that melatonin decreases the time to get to sleep (lag-phase), whilst increasing the amount of time a person stays asleep.
Cortisol, The Stress Hormone
Cortisol is a glucocorticoid hormone that is essential for life. It is produced by the adrenal glands and is often referred to as the “stress hormone”, since it is raised by stress and involved in the body’s response to it.
Cortisol is involved in many functions of the body including central nervous system (CNS) stimulation, blood sugar regulation, and immune system modulation. When deficiencies or excess of this steroid hormone occur many symptoms and health conditions are experienced. Addison’s disease and Cushing’s disease are the most well-known conditions associated with cortisol deficiency and excess respectively. Although they are life-threatening
diseases, they are rare. More mild adrenal imbalances however may be more common and give rise to many health complaints. For more information see the adrenal function test profiles.
