NOTE: This test is ONLY AVAILABLE TO AUSTRALIAN RESIDENTS.
M2 Pyruvate Kinase (M2-PK), as measured in faeces, is a tumour marker for colorectal cancer. Though M2-PK can be elevated in many tumour types, rather than being an organ-specific tumour marker, increased stool (faecal) levels can be used as a early detection of colorectal carcinomas.
The detection of M2-PK does not depend on blood in the stool and is specifically related to changes in tumour metabolism. The M2-PK test is a non-invasive stool test that can be used for the early detection of colorectal cancers and polyps which are known to be the precursors of colorectal cancer.
Increased M2-PK values can sometimes also occur in severe inflammatory diseases which must be excluded by differential diagnosis. If elevated levels of M2PK are present, it is recommended to request more specific tumour marker tests such as (CEA) for bowel cancer, CA 19-9 for pancreatic cancer and CA 72-4 for gastric cancer. This will significantly increase the sensitivity to detect various cancers.
M2PK can be ordered as a single marker or in alliance with a CDSA panel that includes certain GIT markers.
Analytes
M2 Pyruvate Kinase (M2-PK)
Test Method
EIA (Enzyme immunoassay)
Common Conditions:
- Gastrointestinal and Digestive Health
- Bloating, pain or nausea
- Cholecystectomy
- Gastroesophageal reflux symptoms
- Loose or watery stools
- Undigested food in the stool
- Endocrine and Hormonal Health
- Diabetes
- Hypochlorhydria
- Other Health Conditions
- Food intolerances
- Osteoporosis
About The Test
All tests come with full instructions, including a pre-authorised practitioner script.
Home test kits come with everything you need to complete the test, including free express post return postage to the laboratory.
All pathology test kits come with a preauthorised script (including test kit/s if required) to take to your local pathology test centre.
You can click here to find a pathology near you.
Turn-around time: 3–5 days
