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MegaMucosa (180 Capsules)


Availability: 26 in stock


Megamucosa is also available in a powder, click here.

MegaMucosa is the first complete mucosal support supplement of its kind, formulated to REBUILD a healthy mucosal barrier. MegaMucosa also contains dairy-free immunoglobulins clinically shown to support a healthy immune response in the mucosa and a state-of-the-art flavobiotic shown to support microbial diversity and alleviate barrier dysfunction, otherwise known as leaky gut.

The first complete mucosal support that works!

MegaMucosa is the complete mucosal support supplement of its kind, formulated to REBUILD a healthy mucosal barrier.

MegaMucosa also contains dairy-free immunoglobulins shown to support a healthy immune response in the mucosa and a state-of-the-art flavobiotic clinically shown to support microbial diversity and alleviate barrier dysfunction, otherwise known as leaky gut.

The mucosal system is a very important part of the human immune system. Not many people think of mucus as being protective, but it is the main interface between the human body and the outside world. The mucosal system contains 150 times more surface area than the skin, which makes it one of the most important immune barriers. The health of the mucosa determines how the body interacts with antigens; therefore, the integrity of the intestinal mucosa can dictate overall immune function.

kiran Krishnan(Microbiome labs): “Megamucosa it’s a mucosa support formula, now when you look at the intestinal lining where a lot of disease starts, it happens in the breakdown of the mucosa, so the mucosa is an actual physical barrier that separates the outside world which is the lumen of the intestines from the inside world which is when things are allowed to get passed the intestinal lining and enter the circulation”.

That mucosal barrier is the defense system and also the immune sampling for everything that is entering the body, now most people don’t know that the mucosal system of the body has over 150 more time the surface area than the dermal system (the skin), we always think of our dermal system (our skin) as our biggest area but it is in fact the mucosal system”.

“And everything starts in the mucosal system when it comes to the inflammatory breakdown in response to the environment that includes environmental toxins, food, bacteria, viruses and so on”.


“So it becomes paramount to make sure we are dealing with or have a healthy mucosal layer, now the mucosal layer is made up from something called glycoprotein which is a mix between sugar and amino acid which is the building block of the mucosa”.

“Even though we can use probiotics and prebiotics to stimulate the rebuilding of the mucosa…


if you don’t provide the building blocks your body won’t be able to rebuild your mucosa”.

“So one of the main components of the megamucosa is that we have added these essential amino acids, there are 4 essential amino acids that go into the product to act as the building blocks, a study has shown that with the addition of those amino acids when you damaged the mucosal lining it increases the growth of the mucosal lining the repair of the mucosal lining by 95% compared to not providing those specific amino acids”.

“Now, on top of that you need to modulate the immune response and that’s where we have selected a very well studied bovine IgG, this is an immunoglobulin specifically the IgG version that studies show helps reduce inflammation in the intestinal lining, it helps modulate the immune response to bacteria, viruses, toxins, food particles which allows for the minimizing of the damage to the mucosa which then allows the mucosa to regenerate and rebuild”.

“So megamucosa becomes a very very essential part of total gut restoration because you can fix the microbiome, you can fix the leakiness of the gut but if you don’t have an effective mucosal layer you are not going to solve the problem.”

What does it do?

The dairy-free immunoglobulin concentrate supports healthy digestion, neutralizes environmental toxins, and helps to REBUILD protective intestinal barriers. These IgG antibodies can reduce the damage of metabolic endotoxemia and neutralize LPS, an endotoxin that triggers mucosal activation.

There are four key amino acids that play an important role in the production of intestinal mucosa include: L-proline, L-serine, L-cysteine, and L-threonine. These four amino acids have been shown to increase mucin2 production and stimulate mucin synthesis in the colon, resulting in a thicker and healthier mucosal barrier.

MicrobiomeX® is a natural citrus extract rich in polyphenols that support digestive health and immunity by increasing microbial diversity in the gut and maintaining healthy gut barrier function. A clinical study using 500mg of citrus fruit extract found a significant increase in short-chain fatty acid (SCFA) composition, suggesting that these polyphenols may help modulate the microbial composition in the gut.

Why rebuild your intestinal barrier?

One of the biggest health risks of today is intestinal permeability and or leaky gut syndrome.  Leaky gut syndrome is a condition where your intestinal tract becomes leaky, in other words, the intestinal wall becomes weak allowing toxins, waste products, and undigested foods to pass through the intestinal wall and into your bloodstream which causes a great deal of distress to your body, your organs, unsets your immune system and your health leading to serious diseases including most autoimmune diseases.

The truth is without a healthy intestinal track you can lose your ability to properly absorb essential nutrients that defend against death-related diseases.


The biggest problem with increased intestinal permeability is that once it starts it causes a chain reaction of events that make it hard for the body to repair the problem.  Once the lining of the intestinal wall becomes damaged and allows toxic substances to pass through to the bloodstream other organs such as the liver, kidney and immune system are now under great pressure to attempt to clean up the mess, this causes a vicious cycle, especially with the liver and immune system.

Causes of leaky gut & Intestinal permeability

So what causes a leaky gut you may wonder, well there is no one answer, intestinal permeability is one the most important parts of not only digestion but also of nutrition, increased permeability of the intestine leads to reduced intake of essential nutrients, and this happens because essential nutrients are not digested properly making the nutrients unusable, so when you have leaky gut you will also have nutritional deficiencies.  When the permeability becomes increased that’s when the problems start.  We know that a leaky gut is a result of many contributing factors here are just some of the more common causes:

  • Alcohol
  • Antibiotics
  • Anti-inflammatory drugs
  • Chemotherapy, radiotherapy
  • Dysbiosis (imbalance of good and bad bacteria)
  • Food allergies
  • Gastrointestinal disease
  • Genetic mutations
  • heavy metal toxicity
  • Infections of bacteria, viruses, yeasts & parasites.
  • Long term stress
  • Low fiber diet
  • Nutritional deficiencies
  • Poor digestion
  • Secretory IgA deficiency
  • Toxic substances

Not sure if you need megamucosa?

If you are not sure if mucosa complete mucosal support supplement support is for you the best way to find out is to check the signs and symptoms of the leaky gut syndrome and or get your intestinal permeability tested using a simple at-home urine test.

NOTE:  This product is Bovine-Based.  Do not consume if you have a beef allergy.

NOTE:  This product works even better when combined with Megasporebiotic, click here to learn more.

Weight 200 g
Dimensions 6 × 6 × 13.5 cm